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Acid gel tabs

$350.00$600.00

DOSAGE AND ADMINISTRATION

The preferable method of use is to apply Salicylic Acid 6% Gel thoroughly to the affected area and occlude the area at night.

Preferably, the skin should be hydrated for at least five minutes before application.

The medication is wash off in the morning and if excessive drying and/or irritation is observe a bland cream or lotion may be applied.

Once clearing is apparent, the occasional use of Acid gel tabs will usually maintain the remission.

In those areas where occlusion is difficult or impossible, application may be made more frequently;

hydration by wet packs or baths prior to application apparently enhances the effect.

Unless hands are being treated, hands should be rinsed thoroughly after application.

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Description

ACID GEL TABS

Acid gel tabs is apply topically and use in the removal of excessive keratin in hyperkeratotic skin disorders.

Each gram of Salicylic Acid 6% Gel contains salicylic acid 6% as the active ingredient, and

the following inactive ingredients: hydroxypropylcellulose and propylene glycol.

Gel acid tab  produce desquamation of the horny layer of skin

while not affecting qualitative or quantitative changes in structure of the viable epidermis.

The mechanism of action has attributes in dissolution of intercellular cement substance. 

 In a study of the percutaneous absorption of salicylic acid from Salicylic Acid 6% Gel in four patients with extensive active psoriasis,

Taylor and Halprin identify  that peak serum salicylate levels never exceed 5 mg/100 mL even though more than 60% of the  salicylic acid apply was absorb.

Systemic toxic reactions are usually associated with much higher serum levels (30 to 40 mg/100mL).

Peak serum levels occur within 5 hours of the topical application under occlusion.

The sites were occluded for 10 hours over the entire body surface below the neck.

Since salicylates are distributed in the extracellular space, patients with a contracted extracellular space due to dehydration

or diuretics have higher salicylate levels than those with a normal extracellular space.

The major metabolites identify in the urine after topical administration are salicyluric acid (52%), salicylate glucuronides (42%), and free salicylic acid (6%). 

The urinary metabolites after percutaneous absorption differ from those after oral salicylate administration;

those derive from percutaneous absorption contain more glucuronides and less salicyluric and salicylic acid.

Almost 95% of a single dose of salicylate is sent out within 24 hours of its entrance into the extracellular space. 

WARNINGS WHEN USING SALICYCLIC ACID GEL TABS

You should avoid contact with eyes, lips, broken or swollen skin, and all mucous membranes .

Prolong use over large areas, especially in children and those patients with significant renal or hepatic impairment could result in salicylism.

Concomitant use of other drugs which may contribute to elevate serum salicylate levels should be avoided where the potential for toxicity is present.

In children under 12 years of age and those patients with renal or hepatic impairment,

the disrupt area should be distinct and the patient should be monitored constantly to avoid salicylate toxicity:

nausea, vomiting, dizziness, loss of hearing, tinnitus, lethargy, hyperpnoea, diarrhea, psychic disturbances.

In the event of salicylic acid toxicity, the use of Salicylic Acid 6% Gel should be stop.

Fluids should be given to promote urinary excretion.

Treatment with sodium bicarbonate (oral or intravenous) should be done as appropriate.

Considering the potential of developing Reye’s syndrome, salicylate products should not be given to children or teenagers with varicella or influenza, unless directed by a physician.

DOSAGE AND ADMINISTRATION

The preferable method of use is to apply Salicylic Acid 6% Gel thoroughly to the disrupt area and occlude the area at night.

Preferably, the skin should be wet for at least five minutes before application.

The medication is wash off in the morning and if excessive drying and/or irritation is observe a bland cream or lotion may be apply.

Once clearing is apparent, the occasional use of Acid gel tabs will usually maintain the remission.

In those areas where occlusion is difficult or impossible, application may be made more frequently;

wetting the areas of application before application of the acid gel tabs enhance the effects

you should rinse your hands thoroughly after application, except you treat your hands.

HOW SALICYCLIC ACID IS SUPPLIED

Salicylic Acid 6% Gel is supplied in a 40 gram plastic tube bearing the NDC Number 42192-134-40.

Store at controlled room temperature 15° – 30°C (59° – 86°F). [See USP “Controlled Room Temperature”]

 

Additional information

Qty

20 Tabs, 50 Tabs, 100 Tabs

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